Structural Biology

Andrew C. Kruse

Professor
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Research in the Kruse Lab centers on molecular mechanisms of signal transduction by transmembrane receptors.

... Read more about Andrew C. Kruse

Kruse Laboratory Home Page

Kruse Lab Publications

Seeley G. Mudd Building, Room 232A,
250 Longwood Avenue, Boston, MA 02115

andrew_kruse@hms.harvard.edu

p: 617 432-2246

Mélissa Léger-Abraham

Assistant Professor, Department of Microbiology

My research program focuses on studying specialized translation mechanisms in parasites that significantly burden global health, including, but not limited to, Leishmania, Babesia, and Plasmodium organisms.

Leger-Abraham Laboratory Homepage

Leger-Abraham Lab Publications

77 Avenue Louis Pasteur
Boston, MA 02115

melissa_leger-abraham@hms.harvard.edu

p: 617 432-2418

Ying Lu, Ph.D.

Assistant Professor of Systems Biology
Department of Systems Biology, Harvard Medical School

The Lu lab aims to understand the control of cellular protein degradation, using single-molecule and proteomic approaches.... Read more about Ying Lu, Ph.D.

Lu Laboratory Home Page

Lu Lab Publications

Armenise Building, Room 649
210 Longwood Avenue
Boston, MA 02115

ying_lu@hms.harvard.edu

p: 617 432-5143

Debora S. Marks

Professor, Department of Systems Biology
Harvard Medical School

The overarching goal of my lab is to develop novel statistical methods that combine theory and computation to extract useful information from biological information and provide tools for the whole research community.... Read more about Debora S. Marks

Marks Laboratory Homepage

Marks Lab Publications

Armenise Building, Room 631
200 Longwood Avenue, Boston, MA 02115

debora_marks@ hms.harvard.edu

Leonid A. Mirny, Ph.D.

Professor of Medical Engineering and Science, and Physics
Associate Member of the Broad Institute at Harvard and MIT; and of the Dana-Farber/Harvard Cancer Center
Institute for Medical Engineering and Science, MIT; and Harvard-MIT Division of Health Sciences and Technology

Using computational tools, modeling, and analysis of genomic data to address fundamental problems in biological physics and evolution.... Read more about Leonid A. Mirny, Ph.D.

Mirny Laboratory Home Page

Mirny Laboratory Complete Publications List

Massachusetts Institute of Technology
Building E25, Room 526
45 Carleton Street
Cambridge, MA 02139

leonid@mit.edu

p: 617 452-4862

Danesh Moazed

Professor of Cell Biology
Department of Cell Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute

We are interested in understanding how epigenetic chromatin domains are assembled and stably propagated.

... Read more about Danesh Moazed

Moazed Laboratory Home Page

Moazed Lab Publications

LHRRB Building, Room 517
240 Longwood Avenue, Boston, MA 02115

danesh_moazed@hms.harvard.edu

p: 617 432-1258

Nicholas F. Polizzi

Assistant Professor
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Department of Cancer Biology, Dana-Farber Cancer Institute

Our lab studies protein design and molecular recognition.

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Polizzi Laboratory Webpage

Polizzi Laboratory Publications

450 Brookline Avenue,
Boston, MA 02215

nicholasf_polizzi@dfci.harvard.edu

Tom A. Rapoport, Ph.D.

Professor of Cell Biology, Harvard Medical School
Howard Hughes Investigator

The Rapoport lab studies how proteins move across membranes and how membranes are shaped.... Read more about Tom A. Rapoport, Ph.D.

Rapoport Laboratory Home Page

Dr. Tom Rapoport Profile

Rapoport Lab Publications

Harvard Medical School/ HHMI
Department of Cell Biology
240 Longwood Avenue, Boston, MA 02115

tom_rapoport@hms.harvard.edu

p: 617 432-0637

Eugene I. Shakhnovich

Professor of Chemistry and Chemical Biology, Harvard University

Multiscale Theoretical and Experimental Studies of Physical Chemical Principles of Living Matter.

Shakhnovich Laboratory Home Page

Shakhnovich Lab Publications

Mallinckrodt Building, Room 106
12 Oxford Street, Cambridge, MA 02138

shakhnovich @ chemistry.harvard.edu

p: 617 495-4130

Sichen Susan Shao, Ph.D.

Associate Professor of Cell Biology, Harvard Medical School

We aim to understand the molecular mechanisms that determine the fate of new proteins using in vitro reconstitution, cell biology, and structural biology approaches.... Read more about Sichen Susan Shao, Ph.D.

Shao Laboratory Home Page

Shao Lab Publications

Department of Cell Biology
240 Longwood Ave.
Building C, Room 451
Boston, MA 02115

sichen_shao@hms.harvard.edu

p: 617 432-1067

William M. Shih

Professor, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Professor, Department of Cancer Biology, Dana-Farber Cancer Institute
Founding Core Faculty, Wyss Institute at Harvard University

Research in the Shih laboratory focuses on design of self-assembling biomolecular machines and their diagnostic and therapeutic applications.

... Read more about William M. Shih

Shih Laboratory Home Page

Shih Lab Publications

Dana-Farber Cancer Institute:
Longwood Center, LC3313
360 Longwood Avenue, Boston, MA 02215

Wyss Center:
Ctr. for Life Science Bldg. Room 541,
3 Blackfan Circle, Boston MA 02115

william.shih @ wyss.harvard.edu

p: 617 632-5143

Timothy A. Springer, Ph.D.

Latham Family Professor, Professor of Biological Chemistry and Molecular Pharmacology, Professor of Medicine, Harvard Medical School
Program in Cellular and Moleculr Medicine, Division of Hematology/ Oncology, Department of Medicine, Boston Children's Hospital

We study receptor-ligand interactions and transmembrane signal transmission that are relevant to immunology, hemostasis, and human disease using structural, cell biological, and single molecule techniques.

Springer Laboratory Home Page

Springer Lab Publications

Program in Cellular and Molecular Medicine
Center for Life Sciences Building
Boston Children's Hospital
3 Blackfan Circle, Room 3103
Boston, MA 02115

springer @ crystal.harvard.edu

p: 617 713-8200

Gerhard Wagner

Elkan Rogers Blout Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Our research is focused on protein structure, dynamics and stability, and on the relation of these to protein function using NMR and computational techniques as the main tools used to address these problems.... Read more about Gerhard Wagner

Wagner Laboratory Home Page

Wagner Lab Publications

Harvard Medical School, Building C1, Room 112
240 Longwood Avenue, Boston, MA 02115

wagner@hms.harvard.edu

p: 617 432-3213

Johannes C. Walter

Professor, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Howard Hughes Medical Institute Investigator

DNA replication and repair mechanisms that suppress genomic instability.

... Read more about Johannes C. Walter

Walter Laboratory Home Page

Walter Lab Publications

Building C2, Room 266A
240 Longwood Avenue
Boston, MA 02115

johannes_walter@hms.harvard.edu

p: 617 432-4799

Hao Wu, Ph.D.

Asa and Patricia Springer Professor, Department of Biological Chemistry and Molecular Pharmacology
Department of Pediatrics, Harvard Medical School
Senior Investigator, Program in Cellular and Molecular Medicine, Boston Children’s Hospital

The Wu laboratory of mechanistic immunology focuses on elucidating cellular and structural regulation in innate immune pathways, in particular the inflammasome pathway.... Read more about Hao Wu, Ph.D.

Wu Laboratory Home Page

Wu Lab Publications

Immune Disease Institute,
Center for Life Sciences Building
3 Blackfan Circle, 3rd Floor, Room 3099
Boston, MA 02115

hao.wu@childrens.harvard.edu

p: 617 713-8160 f: 617 713-8161

The Harvard Biophysics Graduate Program

PhD Research at the Interface of Quantitative Science and Biology