Structural Biology

Jonathan Abraham Photo

Jonathan Abraham, M.D., Ph.D.

Associate Professor
Department of Microbiology, Harvard Medical School

We use methods in molecular biology, immunology, and structural biology to study host-pathogen interactions, with the goal of informing strategies aimed at treating or preventing infection.

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New Research Building, Room 939L
77 Avenue Louis Pasteur
Boston, MA 02115
p: 617 432-5388
Stephen C. Blacklow, M.D., Ph.D.

Stephen C. Blacklow, M.D., Ph.D.

Gustavus Adolphus Pfeiffer Professor
Chair, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Member, Department of Cancer Biology, Dana Farber Cancer Institute

The Blacklow laboratory studies biochemical and molecular mechanisms of signal transduction. A major focus is on elucidating key events mediated by the Notch signaling pathway in health and disease.... Read more about Stephen C. Blacklow, M.D., Ph.D.

Harvard Medical School
LHRRB Building, Room 201B
45 Shattuck Street, Boston, MA 02115
p: 617 432-5176
Luke Chao Photo

Luke H. Chao (He/ Him/ His)

Assistant Professor
Department of Molecular Biology, Massachusetts General Hospital
Department of Genetics, Harvard Medical School
Our group is interested in understanding the structural and biophysical determinants of membrane morphology. Active areas of interest include: mitochondrial dynamics (and cristae morphology), bacterial ultrastructure, and plasma membrane projections.... Read more about Luke H. Chao (He/ Him/ His)
185 Cambridge Street, Simches Research Building, CPZN 6.808
Boston, MA 02114
p: (617) 724-2323
Josefina del Marmol Photo

Josefina del Marmol (She/ Her/ Hers)

Assistant Professor
Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Our lab studies the molecular mechanisms of sensory transduction, seeking to understand how animals detect the physical and chemical cues from their environment and transform them into cellular signals. In particular, we focus on the sense of smell in insect vectors of disease.

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240 Longwood Avenue,
Building C, Room 210
Boston, MA 02115
Harvard Medical School Campus
Steve Harrison Photo

Stephen C. Harrison

Giovanni Armenise-Harvard Professor of Basic Medical Sciences
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Boston Children's Hospital
Investigator, Howard Hughes Medical Institute
The overall objective of our research is to understand how protein interactions determine subcellular structure. We use direct structural approaches – principally X-ray crystallography, often in combination with electron microscopy – to determine the atomic organization of macromolecular complexes.... Read more about Stephen C. Harrison
Harvard Medical School
Seeley G. Mudd Building, Room 130,
250 Longwood Avenue, Boston, MA 02115
and
HHMI Laboratory of Molecular Medicine
Enders Research Building, Children's Hospital
320 Longwood Avenue, Boston, MA 02115
p: 617 432-5609
Doeke Hekstra Photo

Doeke Romke Hekstra

Assistant Professor of Moelcular and Cellular Biology
Department of Molecular and Cellular Biology, Harvard University
The central aim of my current research is to understand the mechanical basis of protein function, that is, the collective motions and the forces that guide these motions, enabling the conformational and energetic changes required for functional transitions.... Read more about Doeke Romke Hekstra
Northwest Building, Room 311.11
52 Oxford Street,
Cambridge, MA 02138
p: 617 496-4740
Sun Hur Photo

Sun Hur, Ph.D. (She/ Her/ Hers)

Oscar M. Schloss, MD Professor of Pediatrics
Professor, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Program in Cellular and Molecular Medicine, Children's Hospital Boston

Our laboratory investigates the molecular mechanisms of the vertebrate immune system.

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Immune Disease Institute,
Center for Life Sciences Building, Room 3095
3 Blackfan Circle, Boston, MA 02115
p: 617 713-8250