Structural Biology

Jonathan Abraham Photo

Jonathan Abraham, M.D., Ph.D.

Member of the Faculty
Department of Microbiology and Immunobiology, Harvard Medical School

Our laboratory seeks to understand at the molecular level how the human body tackles infections by agents that cause highly lethal human diseases that have limited treatment or vaccine options.

... Read more about Jonathan Abraham, M.D., Ph.D.
New Research Building, Room 939L
77 Avenue Louis Pasteur
Boston, MA 02115
p: 617 432-5388
Howard Berg, Ph.D.

Howard Berg, Ph.D.

Herchel Smith Professor of Physics, Harvard University
Professor of Molecular and Cellular Biology, Department of Molecular and Cellular Biology
Member, Rowland Institute for Science

 

Our quest is an understanding of the behavior of bacteria at the molecular level, especially behavior involving chemical stimuli (chemotaxis)... Read more about Howard Berg, Ph.D.

Biological Laboratories Building, Room 3063
16 Divinity Avenue, Cambridge, MA 02138
p: 617 495-0924 fax: 617 496-1114
Stephen C. Blacklow, M.D., Ph.D.

Stephen C. Blacklow, M.D., Ph.D.

Gustavus Adolphus Pfeiffer Professor
Chair, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Member, Department of Cancer Biology, Dana Farber Cancer Institute

The Blacklow laboratory studies biochemical and molecular mechanisms of signal transduction. A major focus is on elucidating key events mediated by the Notch signaling pathway in health and disease.... Read more about Stephen C. Blacklow, M.D., Ph.D.

Harvard Medical School
LHRRB Building, Room 201B
45 Shattuck Street, Boston, MA 02115
p: 617 432-5176
Martha Bulyk Photo

Martha L. Bulyk

Professor of Medicine and Pathology, Harvard Medical School
Division of Genetics, Brigham & Women's Hospital
Co-Chair, Harvard Biophysics Graduate Program

Transcription factors and DNA regulatory elements.... Read more about Martha L. Bulyk

Division of Genetics, Dept. of Medicine
Brigham & Women's Hospital and Harvard Medical School
HMS New Research Building, Room 466D (4th Floor)
77 Avenue Louis Pasteur, Boston, MA 02115
p: 617 525-4725
Luke Chao

Luke H. Chao

Assistant Professor
Department of Molecular Biology, Massachusetts General Hospital
Department of Genetics, Harvard Medical School
Organelle structure-function: We investigate how proteins self-organize in the birth, life and death of cellular compartments. Our goal is to understand how coupled, coordinated Ångstrom-scale motions propagate into micron-scale cellular rearrangements. ... Read more about Luke H. Chao
185 Cambridge Street, Simches Research Building, CPZN 6.808
Boston, MA 02114
p: (617) 724-2323

Stephen C. Harrison

Giovanni Armenise-Harvard Professor of Basic Medical Sciences
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Boston Children's Hospital
Investigator, Howard Hughes Medical Institute
The overall objective of our research is to understand how protein interactions determine subcellular structure. We use direct structural approaches – principally X-ray crystallography, often in combination with electron microscopy, – to determine the atomic organization of macromolecular complexes.... Read more about Stephen C. Harrison
Harvard Medical School
Seeley G. Mudd Building, Room 130,
250 Longwood Avenue, Boston, MA 02115
and
HHMI Laboratory of Molecular Medicine
Enders Research Building, Children's Hospital
320 Longwood Avenue, Boston, MA 02115
p: 617 432-5609
Doeke Hekstra Photo

Doeke Romke Hekstra

Assistant Professor of Moelcular and Cellular Biology
Department of Molecular and Cellular Biology, Harvard University
The central aim of my current research is to understand the mechanical basis of protein function, that is, the collective motions and the forces that guide these motions, enabling the conformational and energetic changes required for functional transitions.... Read more about Doeke Romke Hekstra
Northwest Building, Room 311.11
52 Oxford Street,
Cambridge, MA 02138
p: 617 496-4740
Sun Hur Photo

Sun Hur

Associate Professor
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Program in Cellular and Molecular Medicine, Children's Hospital Boston

Our laboratory investigates the molecular mechanisms of the vertebrate immune system.

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Immune Disease Institute,
Center for Life Sciences Building, Room 3095
3 Blackfan Circle, Boston, MA 02115
p: 617 713-8250