Structural Biology

Jonathan Abraham, M.D., Ph.D.

Member of the Faculty
Department of Microbiology and Immunobiology, Harvard Medical School

Our laboratory seeks to understand at the molecular level how the human body tackles infections by agents that cause highly lethal human diseases that have limited treatment or vaccine options.

Harvard DICP Profile

Abraham Laboratory Home Page

New Research Building, Room 939L
77 Avenue Louis Pasteur
Boston, MA 02115

abraham@crystal.harvard.edu

p: 617 432-5388

Haribabu Arthanari, Ph.D.

Assistant Professor
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Department of Cancer Biology, Dana-Farber Cancer Institute

Therapeutic Targeting of Protein-Protein Interactions.... Read more about Haribabu Arthanari, Ph.D.

Arthanari Laboratory Homepage

Harvard Medical School
Longwood Center, LC-3311
360 Longwood Avenue,
Boston, MA 02115

hari_arthanari@hms.harvard.edu

p: 617 632-6422

Howard Berg, Ph.D.

Herchel Smith Professor of Physics, Harvard University
Professor of Molecular and Cellular Biology, Department of Molecular and Cellular Biology
Member, Rowland Institute for Science

Our quest is an understanding of the behavior of bacteria at the molecular level, especially behavior involving chemical stimuli (chemotaxis)... Read more about Howard Berg, Ph.D.

Berg Laboratory Home Page

Biological Laboratories Building, Room 3063
16 Divinity Avenue, Cambridge, MA 02138

hberg@mcb.harvard.edu

p: 617 495-0924 fax: 617 496-1114

Stephen C. Blacklow, M.D., Ph.D.

Gustavus Adolphus Pfeiffer Professor
Chair, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Member, Department of Cancer Biology, Dana Farber Cancer Institute

The Blacklow laboratory studies biochemical and molecular mechanisms of signal transduction. A major focus is on elucidating key events mediated by the Notch signaling pathway in health and disease.... Read more about Stephen C. Blacklow, M.D., Ph.D.

Blacklow Laboratory Home Page

BCMP Department Home Page

Harvard Medical School
LHRRB Building, Room 201B
45 Shattuck Street, Boston, MA 02115

p: 617 432-5176

Alan Brown

Assistant Professor
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

The long-term goal of the Brown laboratory is to understand the structure and function of cilia (also known as eukaryotic flagella). ... Read more about Alan Brown

Brown Laboratory Home Page

Department of BCMP
Building C, Rm 249A,
240 Longwood Avenue,
Boston, MA 02115

alan_brown@hms.harvard.edu

Martha L. Bulyk

Professor of Medicine and Pathology, Harvard Medical School
Division of Genetics, Brigham & Women's Hospital
Co-Chair, Harvard Biophysics Graduate Program

Transcription factors and DNA regulatory elements.... Read more about Martha L. Bulyk

Bulyk Laboratory Home Page

Division of Genetics, Dept. of Medicine
Brigham & Women's Hospital and Harvard Medical School
HMS New Research Building, Room 466D (4th Floor)
77 Avenue Louis Pasteur, Boston, MA 02115

mlbulyk@genetics.med.harvard.edu

p: 617 525-4725

Luke H. Chao

Assistant Professor
Department of Molecular Biology, Massachusetts General Hospital
Department of Genetics, Harvard Medical School

Organelle structure-function: We investigate how proteins self-organize in the birth, life and death of cellular compartments. Our goal is to understand how coupled, coordinated Ångstrom-scale motions propagate into micron-scale cellular rearrangements. ... Read more about Luke H. Chao

Chao Laboratory Home Page

185 Cambridge Street, Simches Research Building, CPZN 6.808
Boston, MA 02114

chao@molbio.mgh.harvard.edu

p: (617) 724-2323

James J. Chou

Professor, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Transmembrane Signaling and Transport.... Read more about James J. Chou

Chou Laboratory Home Page

Harvard Medical School
Seeley G. Mudd Bldg., Room 109
240 Longwood Avenue
Boston, MA 02115

james_chou@hms.harvard.edu

p: 617 432-2920

Min Dong, Ph.D.

Associate Professor
Dept. of Urology, Boston Children's Hospital
Dept. of Microbiology and Immunobiology, Harvard Medical School

Bacterial toxin biology, therapeutics, and mechanism of membrane trafficking... Read more about Min Dong, Ph.D.

Dong Laboratory Home Page

Dr. Min Dong Profile

Dong Laboratory Publications

Enders Building, Room 1070
Boston Children's Hospital
300 Longwood Ave.,
Boston, MA 02115

min.dong@children's.harvard.edu

p: 857 218-4232

Rachelle Gaudet, Ph.D.

Professor of Molecular and Cellular Biology
Department of Molecular and Cellular Biology, Harvard University

Structural biology of signaling and transport through biological membranes.... Read more about Rachelle Gaudet, Ph.D.

Gaudet Laboratory Home Page

52 Oxford Street
Northwest lab Bldg., Rm 311.13
Cambridge, MA 02138

gaudet@mcb.harvard.edu

p: 617 495-5616

Stephen C. Harrison

Giovanni Armenise-Harvard Professor of Basic Medical Sciences
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Boston Children's Hospital
Investigator, Howard Hughes Medical Institute

The overall objective of our research is to understand how protein interactions determine subcellular structure. We use direct structural approaches – principally X-ray crystallography, often in combination with electron microscopy, – to determine the atomic organization of macromolecular complexes.... Read more about Stephen C. Harrison

Harrison Laboratory Home Page

Harrison Laboratory Publications

Harvard Medical School
Seeley G. Mudd Building, Room 130,
250 Longwood Avenue, Boston, MA 02115
and
HHMI Laboratory of Molecular Medicine
Enders Research Building, Children's Hospital
320 Longwood Avenue, Boston, MA 02115

schadmin@crystal.harvard.edu

p: 617 432-5609

Doeke Romke Hekstra

Assistant Professor of Moelcular and Cellular Biology
Department of Molecular and Cellular Biology, Harvard University

The central aim of my current research is to understand the mechanical basis of protein function, that is, the collective motions and the forces that guide these motions, enabling the conformational and energetic changes required for functional transitions.... Read more about Doeke Romke Hekstra

Hekstra Laboratory Website

Northwest Building, Room 311.11
52 Oxford Street,
Cambridge, MA 02138

doeke_hekstra@harvard.edu

p: 617 496-4740

Sun Hur

Associate Professor
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Program in Cellular and Molecular Medicine, Children's Hospital Boston

Our laboratory investigates the molecular mechanisms of the vertebrate immune system.

... Read more about Sun Hur

Hur Laboratory Home Page

Immune Disease Institute,
Center for Life Sciences Building, Room 3095
3 Blackfan Circle, Boston, MA 02115

sun.hur@childrens.harvard.edu

p: 617 713-8250

Andrew C. Kruse

Professor
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Research in the Kruse Lab centers on molecular mechanisms of signal transduction by transmembrane receptors.... Read more about Andrew C. Kruse

Kruse Laboratory Home Page

Seeley G. Mudd Building, Room 232A,
250 Longwood Avenue, Boston, MA 02115

andrew_kruse@hms.harvard.edu

p: 617 432-2246

Maofu Liao

Associate Professor
Department of Cell Biology, Harvard Medical School

We use high-resolution cryo-electron microscopy (cryo-EM) to study the structure and function of membrane proteins and DNA-protein machines.... Read more about Maofu Liao

Liao Laboratory Home Page

Liao Laboratory Complete Publications List

HMS, Department of Cell Biology
Seeley G. Mudd Building, Room 509
250 Longwood Avenue, Boston, MA 02115

maofu_liao@hms.harvard.edu

The Harvard Biophysics Graduate Program

PhD Research at the Interface of Quantitative Science and Biology