Single-Molecule Approaches

Stephen C. Blacklow, M.D., Ph.D.

Stephen C. Blacklow, M.D., Ph.D.

Gustavus Adolphus Pfeiffer Professor
Chair, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Member, Department of Cancer Biology, Dana Farber Cancer Institute

The Blacklow laboratory studies biochemical and molecular mechanisms of signal transduction. A major focus is on elucidating key events mediated by the Notch signaling pathway in health and disease.... Read more about Stephen C. Blacklow, M.D., Ph.D.

Harvard Medical School
LHRRB Building, Room 201B
45 Shattuck Street, Boston, MA 02115
p: 617 432-5176
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Stephen Buratowski

Professor of Biological Chemistry and Moelcular Pharmacology
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Member, Harvard Center for Cancer Research

The Buratowski Lab studies eukaryotic gene transcription, chromatin regulation, and RNA processing using a wide range of biochemical, molecular, and genetic techniques.

... Read more about Stephen Buratowski
Building C1, Room 210
Harvard Medical School
240 Longwood Avenue
Boston, MA 02115
p: 617 432-0696
Luke Chao

Luke H. Chao

Assistant Professor
Department of Molecular Biology, Massachusetts General Hospital
Department of Genetics, Harvard Medical School
Organelle structure-function: We investigate how proteins self-organize in the birth, life and death of cellular compartments. Our goal is to understand how coupled, coordinated Ångstrom-scale motions propagate into micron-scale cellular rearrangements. ... Read more about Luke H. Chao
185 Cambridge Street, Simches Research Building, CPZN 6.808
Boston, MA 02114
p: (617) 724-2323
L. Stirling Churchman

L. Stirling Churchman

Associate Professor of Genetics
Harvard Medical School
Associate Member of the Broad Institute of Harvard and MIT

High-resolution global studies to elucidate the molecular mechanisms that control the expression of both the nuclear and mitochondrial genomes.... Read more about L. Stirling Churchman

Department of Genetics, Harvard Medical School
New Research Building, 0356,
77 Avenue Louis Pasteur, Boston, MA 02115
David P. Corey, Ph.D.

David P. Corey, Ph.D.

Bertarelli Professor of Translational Medical Science
Department of Neurobiology, Harvard Medical School

We use a variety of biophysical, structural, genetic and imaging methods to understand the mechanism of sensory transduction by the receptor cells of the inner ear.... Read more about David P. Corey, Ph.D.

Harvard Medical School,
Goldenson Building, Room 443
200 Longwood Avenue, Boston, MA 02115
p: 617 432-2506
Michael Do

Michael T.H. Do

Associate Professor of Neurology, Harvard Medical School
F.M. Kirby Neurobiology Center, Boston Children's Hospital
Center for Brain Science, Harvard University; Division of Sleep Medicine, Brigham & Women's Hospital; Broad Institute, MIT & Harvard
Our lab asks how light drives functions that are as diverse as visual perception, sleep regulation, hormonal control, and setting of the internal body clock.... Read more about Michael T.H. Do
Center for Life Science 12061
3 Blackfan Circle
Boston, MA 02115
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Lene V. Hau

Mallinckrodt Professor of Physics and Applied Physics
Department of Physics, Harvard University
Light-matter interactions, nanoscience, and molecular biology: Experimental studies of protein dynamics at the single-molecule level.... Read more about Lene V. Hau
Lyman Hall Building, Room 229
17 Oxford Street
Cambridge, MA 02138

Lab location: 109-116 & 211-214 Cruft Hall
p: 617 496-5967
Sahand Hormoz

Sahand Hormoz

Assistant Professor
Department of Systems Biology, Harvard Medical School/ Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute
Associate Member, Broad Institute of MIT and Harvard/ Affiliate Faculty, Harvard Stem Cell Institute
We use synthetic biology, single-molecule imaging, and single-cell analysis combined with mathematical modeling to understand the dynamics of cell state transitions in development and disease. ... Read more about Sahand Hormoz
360 Longwood Avenue
Longwood Center Building,
9th Floor, Room 310 (LC-9310)
Boston, MA 02115
p: 617 582-7361
Joseph Loparo

Joseph J. Loparo, Ph.D.

Associate Professor of Biological Chemistry and Molecular Pharmacology
Harvard Medical School

The Loparo laboratory is focused on developing and applying single-molecule methods to study genome maintenance.... Read more about Joseph J. Loparo, Ph.D.

Department of Biological Chemistry and Molecular Pharmacology
Seeley G. Mudd Building, Room 204B
240 Longwood Avenue
Boston, MA 02115
p: 617-432-5586
Alex K. Shalek

Alex K. Shalek

Pfizer-Laubach Career Development Associate Professor
Institute for Medical Engineering & Science and Department of Chemistry, MIT
Ragon Institute/ Broad Institute/ HMS/ MGH

Development and application of new technologies that facilitate understanding of how immune cells collectively perform systems-level functions in health and disease.... Read more about Alex K. Shalek

77 Massachusetts Avenue, Building E25, Room 348a
Massachusetts Institute of Technology
Cambridge, MA 02139
p: 617 324-5670