Single-Molecule Biophysics

Stephen C. Blacklow, M.D., Ph.D.

Gustavus Adolphus Pfeiffer Professor
Chair, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Member, Department of Cancer Biology, Dana Farber Cancer Institute

The Blacklow laboratory studies biochemical and molecular mechanisms of signal transduction. A major focus is on elucidating key events mediated by the Notch signaling pathway in health and disease.... Read more about Stephen C. Blacklow, M.D., Ph.D.

Blacklow Laboratory Home Page

BCMP Department Home Page

Blacklow Lab Publications

Harvard Medical School
LHRRB Building, Room 201B
45 Shattuck Street, Boston, MA 02115

p: 617 432-5176

Stephen Buratowski, Ph.D. (He/ Him/ His)

Professor of Biological Chemistry and Moelcular Pharmacology
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Member, Harvard Center for Cancer Research

The Buratowski Lab studies eukaryotic gene transcription, chromatin regulation, and RNA processing using a wide range of biochemical, molecular, and genetic techniques.

Buratowski Laboratory Homepage

Buratowski Lab Publications

Building C2, Room 347
Harvard Medical School
240 Longwood Avenue
Boston, MA 02115

steveb@hms.harvard.edu

p: 617 432-0696

Adam E. Cohen, Ph.D. (He/ Him/ His)

Professor of Chemistry and Chemical Biology and Physics

Physical tools to study molecules, cells, and organisms.... Read more about Adam E. Cohen, Ph.D. (He/ Him/ His)

Cohen Laboratory Home Page

Cohen Lab Publications

Mallinckrodt Building, Room 115
12 Oxford Street
Cambridge, MA 02138

cohen@chemistry.harvard.edu

p: 617 496-9466

Josefina del Marmol (She/ Her/ Hers)

Assistant Professor
Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Our lab studies the molecular mechanisms of sensory transduction, seeking to understand how animals detect the physical and chemical cues from their environment and transform them into cellular signals. In particular, we focus on the sense of smell in insect vectors of disease.

del Marmol Laboratory Website

del Marmol Publications

240 Longwood Avenue,
Building C, Room 210
Boston, MA 02115
Harvard Medical School Campus

josefina_delmarmol@hms.harvard.edu

Vladimir Denic

Professor of Molecular and Cellular Biology

Molecular Principles Enabling Structural Diversification of Very Long-Chain Fatty Acids.... Read more about Vladimir Denic

Denic Laboratory Home Page

Denic Lab Publications

Northwest Laboratories Bldg., Room 445.3
52 Oxford Street, Cambridge, MA 02138

vdenic@mcb.harvard.edu

Ethan C. Garner

Professor
Department of Molecular and Cellular Biology, Harvard University
Center for Systems Biology

Using in vivo dynamics of single molecules to dissect the mechanisms controlling bacterial shape and growth. ... Read more about Ethan C. Garner

Garner Laboratory Home Page

Garner Lab Publications

Northwest Laboratories Bldg., Room 445.20
52 Oxford Street, Cambridge, MA 02138

egarner@fas.harvard.edu

p: 617 496-8959

Dr. Taekjip Ha (He/ His)

George Yancopoulos in honor of Frederick Alt Professor
Dept. of Pediatrics; Dept. of Biological Chemistry and Molecular Pharmacology
Boston Children's Hospital; Harvard Medical School

Taekjip Ha analyzes single molecules to understand how they act in complex biological systems.

Ha Laboratory Webpage

Ha Laboratory Publications

Enders Building Room 907,
61 Binney Street, Boston
Boston Children's Hospital

Jeffrey R. Holt, PhD

Professor of Otolaryngology & Neurology
F.M. Kirby Neurobiology Center, Boston Children's Hospital

Projects in our lab focus on mechanotransduction or the conversion of mechanical signals into electrical signals in the inner ear.... Read more about Jeffrey R. Holt, PhD

Holt Laboratory Webpage

jeffrey.holt@childrens.harvard.edu

Tomas Kirchhausen

Professor of Cell Biology, Professor of Pediatrics, Harvard Medical School
Springer Family Chair, Boston Children's Hospital

Our objective is to bridge the gap between molecules and cells, either as independent entities in culture, as components of organoids, or as components of living tissues.... Read more about Tomas Kirchhausen

Kirchhausen Laboratory Home Page

Kirchhausen Lab Publications

Harvard Medical School, Program in Cellular and Molecular Medicine,
Warren Alpert Building, Room 133B
200 Longwood Avenue, Boston, MA 02115

kirchhausen@crystal.harvard.edu

p: 617 713-8888

Joseph J. Loparo, Ph.D.

Professor of Biological Chemistry and Molecular Pharmacology
Harvard Medical School

The Loparo laboratory is focused on using biochemical and biophysical tools to study the mechanisms of genome maintenance with molecular resolution.... Read more about Joseph J. Loparo, Ph.D.

Loparo Laboratory Home Page

Loparo Lab Publications

Department of Biological Chemistry and Molecular Pharmacology
Seeley G. Mudd Building, Room 204B
240 Longwood Avenue
Boston, MA 02115

p: 617-432-5586

Ying Lu, Ph.D.

Assistant Professor of Systems Biology
Department of Systems Biology, Harvard Medical School

The Lu lab aims to understand the control of cellular protein degradation, using single-molecule and proteomic approaches.... Read more about Ying Lu, Ph.D.

Lu Laboratory Home Page

Lu Lab Publications

Armenise Building, Room 649
210 Longwood Avenue
Boston, MA 02115

ying_lu@hms.harvard.edu

p: 617 432-5143

Leonid A. Mirny, Ph.D.

Professor of Medical Engineering and Science, and Physics
Associate Member of the Broad Institute at Harvard and MIT; and of the Dana-Farber/Harvard Cancer Center
Institute for Medical Engineering and Science, MIT; and Harvard-MIT Division of Health Sciences and Technology

Using computational tools, modeling, and analysis of genomic data to address fundamental problems in biological physics and evolution.... Read more about Leonid A. Mirny, Ph.D.

Mirny Laboratory Home Page

Mirny Laboratory Complete Publications List

Massachusetts Institute of Technology
Building E25, Room 526
45 Carleton Street
Cambridge, MA 02139

leonid@mit.edu

p: 617 452-4862

Sua Myong, Ph.D. (She/ Her/ Hers)

Professor
Dept. of Pediatrics; Program for Cellular Molecular Medicine
Boston Children's Hospital; Harvard Medical School

We develop and apply single molecule approaches to acquire quantitative understanding of biology and to find ways to improve human medicine.

Myong Laboratory Webpage

Myong Laboratory Publications

Myong Lab PubMed Publications

907 Enders Building,
61 Binney Street, Boston MA 02215
Boston Children's Hospital

Daniel J. Needleman

Gordon McKay Professor of Applied Physics and Professor of Molecular and Cellular Biology
John A. Paulson School of Engineering and Applied Sciences,
Department of Molecular and Cellular Biology, Harvard University

The Needleman laboratory investigates how the cooperative behaviors of molecules give rise to the architecture and dynamics of self-organizing subcellular structures.

... Read more about Daniel J. Needleman

Needleman Laboratory Home page

Needleman Lab Publications

Northwest Laboratory Building, Room 359.20
52 Oxford Street, Cambridge, MA 02138

dneedle@seas.harvard.edu

p: 617 384-6730

Mara G. Prentiss

Mallinckrodt Professor of Physics
Department of Physics, Harvard University

The Prentiss group focuses on using physics tools to elucidate important problems in biology. The basic principles governing self-assembly have been a focus of recent work.

... Read more about Mara G. Prentiss

Prentiss Laboratory Home Page

Prentiss Department Home Page

Prentiss Lab Publications

Lyman Labs Building, Room 222
17 Oxford Street, Cambridge, MA 02138

prentiss@fas.harvard.edu

p: 617 495-2910