Single-Molecule Biophysics

Stephen C. Blacklow, M.D., Ph.D.

Stephen C. Blacklow, M.D., Ph.D.

Gustavus Adolphus Pfeiffer Professor
Chair, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Member, Department of Cancer Biology, Dana Farber Cancer Institute

The Blacklow laboratory studies biochemical and molecular mechanisms of signal transduction. A major focus is on elucidating key events mediated by the Notch signaling pathway in health and disease.... Read more about Stephen C. Blacklow, M.D., Ph.D.

Harvard Medical School
LHRRB Building, Room 201B
45 Shattuck Street, Boston, MA 02115
p: 617 432-5176
Steve Buratowski Photo

Stephen Buratowski, Ph.D. (He/ Him/ His)

Professor of Biological Chemistry and Moelcular Pharmacology
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Member, Harvard Center for Cancer Research

The Buratowski Lab studies eukaryotic gene transcription, chromatin regulation, and RNA processing using a wide range of biochemical, molecular, and genetic techniques.

... Read more about Stephen Buratowski, Ph.D. (He/ Him/ His)
Building C2, Room 347
Harvard Medical School
240 Longwood Avenue
Boston, MA 02115
p: 617 432-0696
Luke Chao Photo

Luke H. Chao

Assistant Professor
Department of Molecular Biology, Massachusetts General Hospital
Department of Genetics, Harvard Medical School
Our group is interested in understanding the structural and biophysical determinants of membrane morphology. Active areas of interest include: mitochondrial dynamics (and cristae morphology), bacterial ultrastructure, and plasma membrane projections.... Read more about Luke H. Chao
185 Cambridge Street, Simches Research Building, CPZN 6.808
Boston, MA 02114
p: (617) 724-2323
Michael Do

Michael T.H. Do

Associate Professor of Neurology, Harvard Medical School
F.M. Kirby Neurobiology Center, Boston Children's Hospital
Center for Brain Science, Harvard University; Division of Sleep Medicine, Brigham & Women's Hospital; Broad Institute, MIT & Harvard
Our lab asks how light drives functions that are as diverse as visual perception, sleep regulation, hormonal control, and setting of the internal body clock.... Read more about Michael T.H. Do
Center for Life Science 12061
3 Blackfan Circle
Boston, MA 02115
Sahand Hormoz

Sahand Hormoz

Assistant Professor
Department of Systems Biology, Harvard Medical School/ Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute
Associate Member, Broad Institute of MIT and Harvard/ Affiliate Faculty, Harvard Stem Cell Institute
We use synthetic biology, single-molecule imaging, and single-cell analysis combined with mathematical modeling to understand the dynamics of cell state transitions in development and disease. ... Read more about Sahand Hormoz
360 Longwood Avenue
Longwood Center Building,
9th Floor, Room 310 (LC-9310)
Boston, MA 02115
p: 617 582-7361
Tom Kirchhausen Photo

Tomas Kirchhausen

Professor of Cell Biology, Professor of Pediatrics, Harvard Medical School
Springer Family Chair, Boston Children's Hospital
Our objective is to bridge the gap between molecules and cells, either as independent entities in culture, as components of organoids, or as components of living tissues.... Read more about Tomas Kirchhausen
Harvard Medical School, Program in Cellular and Molecular Medicine,
Warren Alpert Building, Room 133B
200 Longwood Avenue, Boston, MA 02115
p: 617 713-8888
Max Prigozhin Photo

Maxim Prigozhin, Ph.D. (He/ Him/ His)

Assistant Professor
Department of Molecular and Cellular Biology
Department of Applied Physics, Harvard University

The Prigozhin lab is involved in collaborative and interdisciplinary work in the area of single-cell and single-molecule biophysics of transmembrane signaling. We are particularly interested in cryo-vitrification, all kinds of electron and optical microscopy, and G-protein-coupled receptors. Let us know what you are excited about!... Read more about Maxim Prigozhin, Ph.D. (He/ Him/ His)

Northwest Building, Room 445.20
52 Oxford Street
Cambridge, MA 02138
WesleyWongPhoto

Wesley P. Wong

Associate Professor
Departments of Biological chemistry and Molecular Pharmacology and Pediatrics, Harvard Medical School
Program in Cellular and Molecular Medicine, Boston Children's Hospital
We investigate how force regulates the structure and dynamics of interactions between and within single-molecules, and how this in turn can affect the functioning and malfunctioning of biological systems.  ... Read more about Wesley P. Wong
Children's Hospital Boston, Wyss Institute for Biologically Inspired Engineering
3 Blackfan Circle, 3rd Floor
Boston, MA 02115
p: 617 713-8383
Hao Wu, Ph.D.

Hao Wu, Ph.D.

Asa and Patricia Springer Professor, Department of Biological Chemistry and Molecular Pharmacology
Department of Pediatrics, Harvard Medical School
Senior Investigator, Program in Cellular and Molecular Medicine, Boston Children’s Hospital

The Wu laboratory of mechanistic immunology focuses on elucidating cellular and structural regulation in innate immune pathways, in particular the inflammasome pathway.... Read more about Hao Wu, Ph.D.

Immune Disease Institute,
Center for Life Sciences Building
3 Blackfan Circle, 3rd Floor, Room 3099
Boston, MA 02115
p: 617 713-8160 f: 617 713-8161