I am generally interested in understanding how enzymes operate on a mechanistic level. In the Drennan Lab, I use primarily X-ray crystallography coupled with other biophysical methods to elucidate mechanisms of metalloenzymes. Currently, I am working on a Radical S-adenosylmethionine (SAM) enzyme involved in the biosynthesis of  an antiviral compound. This information will be key in understanding the unique biochemical reactions catalyzed by the Radical SAM enzyme superfamily.