My research seeks to uncover the principles that govern how neural circuits, both biological and artificial, represent and transform information.
A central focus of my group is the geometry of neural population activity, or “neural manifolds,” which...
My research is focused on developing model systems to gain fundamental insights in disease mechanisms within the heart and the brain.
Using induced pluripotent stem cells (iPSCs) and genome editing, we create human disease models caused by ion channels...
Our research studies the molecular mechanisms of cellular fatty acid metabolism and lipid recycling pathways.
A long-term goal of my laboratory is to address mechanisms of cellular fatty acid metabolism and their implication in neuronal functions. Fatty...
Our lab seeks to enable the dissection of tissues into the rules which govern their organization.
Genomic tools for understanding tissue function are critically needed. Applying genomic technologies to tissues has faced three major challenges: first, to...
Our lab studies the molecular mechanisms of sensory transduction, seeking to understand how animals detect the physical and chemical cues from their environment and transform them into cellular signals. In particular, we focus on the sense of smell in...
The focus of my career has been on advancing simultaneous positron emission tomography and magnetic resonance imaging (PET/MRI) toward meaningful clinical human use. Specifically, my efforts have concentrated on developing and validating this novel...
We pose this question for species that occupy distinct ecological niches to learn how...
The Adelman lab studies the changes in gene regulation and epigenetics that drive development and stress-responses.
Cell-type and condition-specific patterns of gene expression are established through a sophisticated network of interactions between...
The Buratowski Lab studies eukaryotic gene transcription, chromatin regulation, and RNA processing using a wide range of biochemical, molecular, and genetic techniques.
The Buratowski lab studies eukaryotic gene expression, focusing on mRNA transcription...
The goal of the Devlin lab is to understand and control the chemistry of human-associated bacteria (i.e., the microbiome) in order to uncover how these bacterial guests affect the human host.
We are not alone. The human body harbors more bacterial cells...