Assembling complex cytoskeletal architectures from simple building blocks.
For a living cell to function properly, its cellular processes must be strictly controlled not only in time but also in space. We are interested in how intracellular spatial...
Using computational tools, modeling, and analysis of genomic data to address fundamental problems in biological physics and evolution.
Our laboratory research focuses on two major projects:
* Understanding 3D genome organization by computer modeling and...
The Wu laboratory of mechanistic immunology focuses on elucidating cellular and structural regulation in innate immune pathways, in particular the inflammasome pathway.
Research Interests:
The Wu laboratory of structural immunology focuses on elucidating...
Physical tools to study molecules, cells, and organisms.
We invent new physical tools to probe biological structures. We use our tools to make new measurements. We choose problems by looking in unexplored regimes of time and space. We combine protein...