We study the neural circuit and molecular basis of individual differences in behavior using custom high-throughput instrumentation, with an eye to its ultimate cause in evolution.
The animal kingdom contains staggering morphological diversity, but even...
Understanding how the brain controls behavior by integrating external sensory information with internal states, such as attention or motivation.
In our lab in the Department of Neurobiology at Harvard Medical School, we worked for many years with non...
Statistical computations and neuronal mechanisms underlying complex decisions and behavior under uncertainty. The work in the lab is theoretical in nature, and we collaborate with experimentalists in a close loop to refine both theories and experiments...
Members of the Zhuang laboratory apply their diverse backgrounds in physics, chemistry, biology, and engineering to develop advanced imaging methods and to exploit these tools to study a variety of interesting biological problems. Understanding the...
The goal of my lab is to understand the role of corticolimbic areas in guiding attention to, and imagery, learning and memory of, motivationally-salient external and interoceptive stimuli.
The way that external stimuli are encoded in brain activity is...
Neural circuits and behavior in larval zebrafish
The general goal of the laboratory is the comprehensive identification and examination of neural circuits controlling behavior using the larval zebrafish as a model system. To that end, we have established...
Physical tools to study molecules, cells, and organisms.
We invent new physical tools to probe biological structures. We use our tools to make new measurements. We choose problems by looking in unexplored regimes of time and space. We combine protein...
Circuits and behavior in C. elegans and DrosophilaAnimals are intrinsically computational. We acquire sensory information about our environments, transform this information into neural representations and memories, and calculate and execute decisions...