Our research explores how we learn from our mistakes. As infants learning to walk, we take unsteady steps, fall, adjust, and eventually develop stable locomotion. This iterative cycle of action, error, and refinement continues throughout life, shaping our...
In our lab, we focus on studying immune regulation through a biophysical lens. Our work is guided by fundamental principles of dynamical systems theory in reaction-diffusion systems.
This enables us to understand how different cell types interact and form...
We develop and apply single molecule approaches to acquire quantitative understanding of biology and to find ways to improve human medicine.
The current directions of our research include investigations of G-quadruplex and R-loop mediated gene...
Taekjip Ha analyzes single molecules to understand how they act in complex biological systems.
Ha and his team combine sophisticated biophysical manipulation techniques with fluorescence imaging to visualize and manipulate protein, RNA, and DNA molecules...
My research is focused on developing model systems to gain fundamental insights in disease mechanisms within the heart and the brain.
Using induced pluripotent stem cells (iPSCs) and genome editing, we create human disease models caused by ion channels...
Projects in our lab focus on mechanotransduction or the conversion of mechanical signals into electrical signals in the inner ear. The process underlies our senses of hearing and balance. We have identified several proteins critical for...
Our lab studies the molecular mechanisms of sensory transduction, seeking to understand how animals detect the physical and chemical cues from their environment and transform them into cellular signals. In particular, we focus on the sense of smell in...
Our DNA represents the full...
In my lab, we apply mass-spectrometry to address biological questions in cancer metabolism, and a major part of our work focuses on technology and method development. Cancer metabolism is a rapidly growing field within the cancer biology scientific...