People

Shamil R. Sunyaev

ssunyaev@rics.bwh.harvard.edu

Professor and Distinguished Chair of Computational Genomics

Division of Genetics, Brigham & Women's Hospital, Harvard Medical School

We are a computational genetics and genomics lab whose main research is on genetic variation, including mechanisms of spontaneous mutagenesis, functional effects of mutations and allelic variants, population genetics and relationship between genotype and...

Gerhard Wagner

wagner@hms.harvard.edu

Elkan Rogers Blout Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Our research is focused on protein structure, dynamics and stability, and on the relation of these to protein function using NMR and computational techniques as the main tools used to address these problems. We are interested in improving NMR methods and...

Lawrence L. Wald

lwald@mgh.harvard.edu

Professor of Radiology, Department of Radiology,

Massachusetts General Hospital, Harvard Medical School

My research centers on the development and application of novel medical imaging techniques (mainly MRI) for the clinical and scientific investigation of the brain diseases and function.The goal is often to increase the sensitivity, scope and utility of...

Johannes C. Walter

johannes_walter@hms.harvard.edu

Professor, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Howard Hughes Medical Institute Investigator

DNA replication and repair mechanisms that suppress genomic instability. Xenopus laevis egg extracts have an extraordinary capacity to recapitulate key events of cell cycle progression in vitro, including DNA replication and repair, mitosis, and...

Amanda Whipple

Amanda_whipple@fas.harvard.edu

Assistant Professor

Department of Molecular and Cellular Biology

Studying RNA chemical modifications that are guided by imprinted non-coding and how differences in the three-dimensional folding of the two parental genomes in offspring impacts imprinted expression and neurodevelopment. Our DNA represents the full...

Wesley P. Wong

wong @ idi.harvard.edu

Associate Professor

Departments of Biological chemistry and Molecular Pharmacology and Pediatrics, Harvard Medical School

Program in Cellular and Molecular Medicine, Boston Children's Hospital

We investigate how force regulates the structure and dynamics of interactions between and within single-molecules, and how this in turn can affect the functioning and malfunctioning of biological systems. Our group is interested in understanding the...

Hao Wu, Ph.D.

hao.wu@childrens.harvard.edu

Asa and Patricia Springer Professor, Department of Biological Chemistry and Molecular Pharmacology

Department of Pediatrics, Harvard Medical School

Senior Investigator, Program in Cellular and Molecular Medicine, Boston Children’s Hospital

The Wu laboratory of mechanistic immunology focuses on elucidating cellular and structural regulation in innate immune pathways, in particular the inflammasome pathway. Research Interests: The Wu laboratory of structural immunology focuses on elucidating...

Gary Yellen

gary_yellen @ hms.harvard.edu

Professor of Neurobiology

Department of Neurobiology, Harvard Medical School

We develop fluorescent biosensors for metabolism, and use quantitative two-photon imaging to learn about the regulation and dynamics of cellular metabolism in brain. Metabolic pathways provide essential energy and building blocks for the function of all...

Peng Yin

py@hms.harvard.edu

Professor of System Biology

Department of Systems Biology, Harvard Medical School

Foundation of Information Directed Molecular Technology: Programming Nucleic Acid Self-Assembly. My research interests lie at the interface of information science, molecular engineering, and biology. We are interested in engineering digitally programmable...

Xin Zhou (She/ Her/ Hers)

Xin_Zhou1@DFCI.harvard.edu

Assistant Professor

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Department of Cancer Biology, Dana-Farber Cancer Institute

My lab designs new protein tools, artificial enzymes, and biomedicines to sense and re-direct cell signaling responses. Molecular recognitions, such as receptor-ligand binding, enzyme-substrate recognition, or metabolite-protein interaction, are...

Xiaowei Zhuang, Ph.D.

David B. Arnold Professor of Science, Howard Hughes Medical Institute Investigator

Department of Chemistry and Chemical Biology

Department of Physics, Harvard University

Members of the Zhuang laboratory apply their diverse backgrounds in physics, chemistry, biology, and engineering to develop advanced imaging methods and to exploit these tools to study a variety of interesting biological problems. Understanding the...