Our lab focuses on the development of adaptive immune responses, protein evolution, and the
interactions between host and pathogen using a combination of biophysical, biochemical, and
molecular virology techniques.
We are primarily protein engineers and...
The Farnung Lab is interested in molecular mechanisms at the interface of transcription and chromatin.
We employ biochemical, biophysical, machine learning, and structural biology approaches to understand how the transcription machinery, histone...
My research program focuses on studying specialized translation mechanisms in parasites that significantly burden global health, including, but not limited to, Leishmania, Babesia, and Plasmodium organisms.
Our efforts notably center on characterizing...
Our lab studies protein design and molecular recognition.
Most proteins function by first binding a ligand, such as another protein, peptide, or small molecule. The Polizzi laboratory aims to learn the rules of protein–ligand binding through the lens...
Projects in our lab focus on mechanotransduction or the conversion of mechanical signals into electrical signals in the inner ear. The process underlies our senses of hearing and balance. We have identified several proteins critical for...
Our lab studies the molecular mechanisms of sensory transduction, seeking to understand how animals detect the physical and chemical cues from their environment and transform them into cellular signals. In particular, we focus on the sense of smell in...
The overarching goal of my lab is to develop novel statistical methods that combine theory and computation to extract useful information from biological information and provide tools for the whole research community.
One million human genomes, will it...
Our proteome is shaped by transcription/translation, as much as by protein degradation. The latter, sometimes even leading to...
We use methods in molecular biology, immunology, and structural biology to study host-pathogen interactions, with the goal of informing strategies aimed at treating or preventing infection.
Several enveloped RNA viruses cause human viral hemorrhagic fevers...
My research interests lie at the interface of information science, molecular engineering, and biology. We are interested in engineering digitally...