The goal of the Devlin lab is to understand and control the chemistry of human-associated bacteria (i.e., the microbiome) in order to uncover how these bacterial guests affect the human host.
We are not alone. The human body harbors more bacterial cells...
Our proteome is shaped by transcription/translation, as much as by protein degradation. The latter, sometimes even leading to...
Our lab studies microbial evolution, primarily of antibiotic resistance, with a goal of developing practical interventions to reduce or reverse resistance.
This will require advances both in technology and in the basic science of resistance evolution...
My research interests lie at the interface of information science, molecular engineering, and biology. We are interested in engineering digitally...
Research in the Shih laboratory focuses on design of self-assembling biomolecular machines and their diagnostic and therapeutic applications.
Tools For Molecular Biophysics:
NMR Structure Determination of Membrane Proteins An outstanding problem in...
To arrive at a decision, organisms must measure multiple environmental signals and interpret them appropriately. The questions we are interested in are how cells and organisms interpret...
Our laboratory is interested in how cell cycle signals regulate chromosome segregation and polarized morphogenesis. Our experimental approaches include a combination of biochemical, genetic and live-cell imaging.
My group studies cell division and...
We are interested in understanding how epigenetic chromatin domains are assembled and stably propagated.
Research in the Moazed lab is focused on the remarkable ability of heterochromatic domains of DNA to heritably silence genes and transposons. These...
We aim to understand the molecular mechanisms that determine the fate of new proteins using in vitro reconstitution, cell biology, and structural biology approaches. Protein biosynthesis is a complex process encompassing translation, protein folding...