My laboratory is interested in the role of spatial organization in host-microbe interactions in the mammalian gut. We develop, extend, and utilize image-based approaches to spatial genomics, including a massively multiplexed single-molecule RNA imaging...
I lead an interdisciplinary research group with interests encompassing computational biology, imaging, and brain science. A core aim of our group is the development of computational methods for biomedical image analysis, with domains ranging from...
We develop and apply single molecule approaches to acquire quantitative understanding of biology and to find ways to improve human medicine.
The current directions of our research include investigations of G-quadruplex and R-loop mediated gene...
The Farnung Lab is interested in molecular mechanisms at the interface of transcription and chromatin.
We employ biochemical, biophysical, machine learning, and structural biology approaches to understand how the transcription machinery, histone...
Our lab seeks to enable the dissection of tissues into the rules which govern their organization.
Genomic tools for understanding tissue function are critically needed. Applying genomic technologies to tissues has faced three major challenges: first, to...
Projects in our lab focus on mechanotransduction or the conversion of mechanical signals into electrical signals in the inner ear. The process underlies our senses of hearing and balance. We have identified several proteins critical for...
Our DNA represents the full...
The overarching goal of my lab is to develop novel statistical methods that combine theory and computation to extract useful information from biological information and provide tools for the whole research community.
One million human genomes, will it...
In my lab, we apply mass-spectrometry to address biological questions in cancer metabolism, and a major part of our work focuses on technology and method development. Cancer metabolism is a rapidly growing field within the cancer biology scientific...
The Buratowski Lab studies eukaryotic gene transcription, chromatin regulation, and RNA processing using a wide range of biochemical, molecular, and genetic techniques.
The Buratowski lab studies eukaryotic gene expression, focusing on mRNA transcription...