Michael A. Levine
2020 PhD Graduate in Biophysics
Dissertation Title: Characterization and Mitigation of Bias in Parametric Mapping of Reward-Induced Dopamine Release using Simultaneous Positron Emission Tomography and Magnetic Resonance Imaging PhD Dissertation Advisor: Dr. Ciprian Catana, Martinos Center for Biomedical Imaging,
Massachsuetts General Hospital For his dissertation research, Michael A. Levine researched medical imaging with Ciprian Catana at Massachusetts General Hospital's Martinos Center. Michael received his undergraduate training at Clemson University (Clemson, SC) in Biomedical Engineering. He worked as a Research Technician in the Quantitative Tumor Imaging at Martinos (QTIM) laboratory for a year before enrolling in the Harvard Biophysics Program and returning to the Martinos Center in the Integrated MR-PET Imaging Laboratory. Michael's dissertation work focused on developing a novel model of dopamine kinetics for use in the study of transient changes in dopamine binding under behavioral challenge. He also worked on unifying PET- and MR-based head motion estimates for the purpose of motion correcting PET reconstruction. Publications: Abstracts: Levine, M.A., Mandeville, J.B., Price, J.C., Catana, C. (2019). Assessment of Model Bias Upon Detection of Dopamine Response to Challenge. Paper presented at Paper presented at ISMRM-SNMMI co-provided workshop on PET/MRI. New York.
Levine, M.A., Chonde, D.B., Chen, K.T., Izquierdo-Garcia, D., Catana, C. (2017). Unification of PET and MR-based Head Motion Estimates for PET Motion Correction. Paper presented at ISMRM-SNMMI co-provided workshop on PET/MRI. Chicago. Levine, M. A., Polaskova, P., Sprinkhuizen, S. M., Stufflebeam, S. M., Rosen, B. R., Kalpathy-Cramer, J., & Gerstner, E. R. (2013). Inter-Vendor Variability in Apparent Diffusion Coefficient Values. Paper presented at the International Society of Magnetic Resonance in Medicine, Salt Lake City. Bowen, S. L., Fuin, N., Levine, M. A., Wey, H., & Catana, C. (2015). Implementation of a Fixed Torus Transmission Scheme for a Simultaneous MR-PET System Paper presented at the IEEE Nuclear Science Symposium & Medical Imaging, San Diego. Gerstner, E. R., Levine, M. A., Ye, X., Mikkelsen, T., Nabors, L. B., Olson, J. J., . . . Grossman, S. A. (2013). A Phase I Study of Cediranib in Combination with Cilengitide in Patients with Recurrent Glioblastoma. Paper presented at the American Society of Clinical Oncology. Journal Articles: Chen KT, Salcedo S, Chonde DB, Izquierdo-Garcia, D., Levine, M. A., Price, J. C., Dickerson, B. C., Catana, C. (2018) MR-assisted PET motion correction in simultaneous PET/MRI studies of dementia subjects. J Magn Reson Imaging. Prentice-Mott, H. V., Meroz, Y., Carlson, A., Levine, M. A., Davidson, M. W., Irimia, D., . . . Shah, J. V. (2016). Directional memory arises from long-lived cytoskeletal asymmetries in polarized chemotactic cells. Proceedings of the National Academy of Sciences, 201513289. doi:10.1073/pnas.1513289113 Bowen, S. L., Fuin, N., Levine, M. A., & Catana, C. (2016). Transmission imaging for integrated PET-MR systems. Physics in Medicine and Biology. 16, 5547. doi: 10.1088/0031-9155/61/15/5547 Gerstner, E. R., Ye, X., Duda, D. G., Levine, M. A., Mikkelsen, T., Kaley, T. J., . . . Grossman, S. (2015). A phase I study of cediranib in combination with cilengitide in patients with recurrent glioblastoma. Neuro Oncol, 17(10), 1386-1392. doi:10.1093/neuonc/nov085
Massachsuetts General Hospital For his dissertation research, Michael A. Levine researched medical imaging with Ciprian Catana at Massachusetts General Hospital's Martinos Center. Michael received his undergraduate training at Clemson University (Clemson, SC) in Biomedical Engineering. He worked as a Research Technician in the Quantitative Tumor Imaging at Martinos (QTIM) laboratory for a year before enrolling in the Harvard Biophysics Program and returning to the Martinos Center in the Integrated MR-PET Imaging Laboratory. Michael's dissertation work focused on developing a novel model of dopamine kinetics for use in the study of transient changes in dopamine binding under behavioral challenge. He also worked on unifying PET- and MR-based head motion estimates for the purpose of motion correcting PET reconstruction. Publications: Abstracts: Levine, M.A., Mandeville, J.B., Price, J.C., Catana, C. (2019). Assessment of Model Bias Upon Detection of Dopamine Response to Challenge. Paper presented at Paper presented at ISMRM-SNMMI co-provided workshop on PET/MRI. New York.
Levine, M.A., Chonde, D.B., Chen, K.T., Izquierdo-Garcia, D., Catana, C. (2017). Unification of PET and MR-based Head Motion Estimates for PET Motion Correction. Paper presented at ISMRM-SNMMI co-provided workshop on PET/MRI. Chicago. Levine, M. A., Polaskova, P., Sprinkhuizen, S. M., Stufflebeam, S. M., Rosen, B. R., Kalpathy-Cramer, J., & Gerstner, E. R. (2013). Inter-Vendor Variability in Apparent Diffusion Coefficient Values. Paper presented at the International Society of Magnetic Resonance in Medicine, Salt Lake City. Bowen, S. L., Fuin, N., Levine, M. A., Wey, H., & Catana, C. (2015). Implementation of a Fixed Torus Transmission Scheme for a Simultaneous MR-PET System Paper presented at the IEEE Nuclear Science Symposium & Medical Imaging, San Diego. Gerstner, E. R., Levine, M. A., Ye, X., Mikkelsen, T., Nabors, L. B., Olson, J. J., . . . Grossman, S. A. (2013). A Phase I Study of Cediranib in Combination with Cilengitide in Patients with Recurrent Glioblastoma. Paper presented at the American Society of Clinical Oncology. Journal Articles: Chen KT, Salcedo S, Chonde DB, Izquierdo-Garcia, D., Levine, M. A., Price, J. C., Dickerson, B. C., Catana, C. (2018) MR-assisted PET motion correction in simultaneous PET/MRI studies of dementia subjects. J Magn Reson Imaging. Prentice-Mott, H. V., Meroz, Y., Carlson, A., Levine, M. A., Davidson, M. W., Irimia, D., . . . Shah, J. V. (2016). Directional memory arises from long-lived cytoskeletal asymmetries in polarized chemotactic cells. Proceedings of the National Academy of Sciences, 201513289. doi:10.1073/pnas.1513289113 Bowen, S. L., Fuin, N., Levine, M. A., & Catana, C. (2016). Transmission imaging for integrated PET-MR systems. Physics in Medicine and Biology. 16, 5547. doi: 10.1088/0031-9155/61/15/5547 Gerstner, E. R., Ye, X., Duda, D. G., Levine, M. A., Mikkelsen, T., Kaley, T. J., . . . Grossman, S. (2015). A phase I study of cediranib in combination with cilengitide in patients with recurrent glioblastoma. Neuro Oncol, 17(10), 1386-1392. doi:10.1093/neuonc/nov085